人 TNFRSF18 (NM_148902) cDNA克隆

基本信息

Accession: NM_148902
基因名称: TNFRSF18
基因别名: AITR; GITR; CD357; GITR-D
基因描述: Homo sapiens tumor necrosis factor receptor superfamily, member 18 (TNFRSF18), transcript variant 3, mRNA.
种属: Human
CDS区长度: 705 (查看编码区序列)
翻译后氨基酸长度: 234 (查看氨基酸序列)
Transcript Variant: This variant (3) contains an extra coding segment, which leads to a frame shift, compared to variant 2. The resulting protein (isoform 3) contains a distinct and shorter C-terminus, as compared to isoform 2.

订购信息

产品编号 产品名称 载体 规格 价格
G166955 人 TNFRSF18 (NM_148902) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TNFRSF18 (NM_004195) cDNA克隆 transcript variant 1
人 TNFRSF18 (NM_148901) cDNA克隆 transcript variant 2
人 TNFRSF18 (NM_148902) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]

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