人 ABCC3 (NM_001144070) cDNA克隆

Accession: NM_001144070
基因名称: ABCC3
基因别名: MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757
基因描述: Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (ABCC3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1719 (查看编码区序列)
翻译后氨基酸长度: 572 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks multiple 3' exons and has an alternate 3' sequence, as compared to variant 1. The resulting isoform (2) is much shorter and has a different C-terminus, as compared to isoform 1.
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G166937 人 ABCC3 (NM_001144070) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]