人 PDE8B (NM_001029852) cDNA克隆

基本信息

Accession: NM_001029852
基因名称: PDE8B
基因别名: ADSD; PPNAD3
基因描述: Homo sapiens phosphodiesterase 8B (PDE8B), transcript variant 5, mRNA.
种属: Human
CDS区长度: 2493 (查看编码区序列)
翻译后氨基酸长度: 830 (查看氨基酸序列)
Transcript Variant: This variant (5), also known as PDE8B3, lacks an alternate in-frame exon compared to variant 1. The encoded isoform (5) is shorter compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G166898 人 PDE8B (NM_001029852) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PDE8B (NM_003719) cDNA克隆 transcript variant 1
人 PDE8B (NM_001029854) cDNA克隆 transcript variant 2
人 PDE8B (NM_001029851) cDNA克隆 transcript variant 3
人 PDE8B (NM_001029853) cDNA克隆 transcript variant 4
人 PDE8B (NM_001029852) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]

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