人 MKNK1 (NM_001135553) cDNA克隆

Accession: NM_001135553
基因名称: MKNK1
基因别名: MNK1
基因描述: Homo sapiens MAP kinase interacting serine/threonine kinase 1 (MKNK1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1275 (查看编码区序列)
翻译后氨基酸长度: 424 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an in-frame coding exon compared to variant 1. This results in a shorter isoform (3) missing an internal protein segment compared to isoform 1.
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G166876 人 MKNK1 (NM_001135553) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]