人 POLR1B (NM_001282779) cDNA克隆

基本信息

Accession: NM_001282779
基因名称: POLR1B
基因别名: RPA2; RPA135; Rpo1-2
基因描述: Homo sapiens polymerase (RNA) I polypeptide B, 128kDa (POLR1B), transcript variant 7, mRNA.
种属: Human
CDS区长度: 2991 (查看编码区序列)
翻译后氨基酸长度: 996 (查看氨基酸序列)
Transcript Variant: This variant (7) uses an alternate splice site in the 5' region, and it thus differs in its 5' UTR and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (6) is shorter at the N-terminus, compared to isoform 1. Both variants 6 and 7 encode isoform 6.

订购信息

产品编号 产品名称 载体 规格 价格
G166474 人 POLR1B (NM_001282779) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 POLR1B (NM_019014) cDNA克隆 transcript variant 1
人 POLR1B (NM_001137604) cDNA克隆 transcript variant 2
人 POLR1B (NM_001282772) cDNA克隆 transcript variant 3
人 POLR1B (NM_001282774) cDNA克隆 transcript variant 4
人 POLR1B (NM_001282776) cDNA克隆 transcript variant 5
人 POLR1B (NM_001282777) cDNA克隆 transcript variant 6
人 POLR1B (NM_001282779) cDNA克隆 transcript variant 7

基因简介

Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM, Mar 2008]

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