人 PLA2G6 (NM_001199562) cDNA克隆

基本信息

Accession: NM_001199562
基因名称: PLA2G6
基因别名: GVI; PLA2; INAD1; NBIA2; iPLA2; NBIA2A; NBIA2B; PARK14; PNPLA9; CaI-PLA2; IPLA2-VIA; iPLA2beta
基因描述: Homo sapiens phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2259 (查看编码区序列)
翻译后氨基酸长度: 752 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and lacks an in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but lacks an internal segment compared to isoform a. Variants 2 and 3 both encode the same isoform (b). Isoform b is found in the cytoplasm while isoform a is membrane-bound.

订购信息

产品编号 产品名称 载体 规格 价格
G166403 人 PLA2G6 (NM_001199562) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PLA2G6 (NM_003560) cDNA克隆 transcript variant 1
人 PLA2G6 (NM_001004426) cDNA克隆 transcript variant 2
人 PLA2G6 (NM_001199562) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010]

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