小鼠 Arfrp1 (NM_001165995) cDNA克隆

基本信息

Accession: NM_001165995
基因名称: Arfrp1
基因别名: AI480700; 1500006I01Rik
基因描述: Mus musculus ADP-ribosylation factor related protein 1 (Arfrp1), transcript variant 4, mRNA.
种属: Mouse
CDS区长度: 465 (查看编码区序列)
翻译后氨基酸长度: 154 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate exon in the 5' region that results in a distinct 5' UTR and causes translation initiation at a downstream start codon, compared to variant 1. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G164609 小鼠 Arfrp1 (NM_001165995) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

小鼠 Arfrp1 (NM_001165991) cDNA克隆 transcript variant 1
小鼠 Arfrp1 (NM_029702) cDNA克隆 transcript variant 2
小鼠 Arfrp1 (NM_001165992) cDNA克隆 transcript variant 3
小鼠 Arfrp1 (NM_001165995) cDNA克隆 transcript variant 4

基因简介

The gene encodes a membrane-associated GTPase that is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) genes. It plays an essential role in Golgi function controlling recruitment of GRIP domain proteins and ARL1 to the trans-Golgi and trans-Golgi to plasma membrane trafficking of cell surface proteins such as E-cadherin. Deletion of this gene in mice leads to embryonic lethality during early gastrulation, which is at least partly caused by the disruption of E-cadherin trafficking to the cell surface and therefore lack of sufficient cell-cell adhesion in the embryo. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

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