人 WEE1 (NM_001143976) cDNA克隆

Accession: NM_001143976
基因名称: WEE1
基因别名: WEE1A; WEE1hu
基因描述: Homo sapiens WEE1 G2 checkpoint kinase (WEE1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1299 (查看编码区序列)
翻译后氨基酸长度: 432 (查看氨基酸序列)
Transcript Variant: This variant (2) has a different first exon and 5' UTR, compared to variant 1. This difference causes translation initiation from an in-frame downstream AUG and an isoform (2) with a shorter N-terminus, compared to isoform 1.
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G163957 人 WEE1 (NM_001143976) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008]