人 UBTF (NM_001076684) cDNA克隆

基本信息

Accession: NM_001076684
基因名称: UBTF
基因别名: UBF; UBF1; UBF-1; NOR-90
基因描述: Homo sapiens upstream binding transcription factor, RNA polymerase I (UBTF), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2184 (查看编码区序列)
翻译后氨基酸长度: 727 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an exon in the coding region, but maintains the reading frame, compared to variant 1. Variants 2 and 3 encode the same isoform (b), which is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G163362 人 UBTF (NM_001076684) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 UBTF (NM_014233) cDNA克隆 transcript variant 1
人 UBTF (NM_001076683) cDNA克隆 transcript variant 2
人 UBTF (NM_001076684) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]

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