人 TFR2 (NM_001206855) cDNA克隆

基本信息

Accession: NM_001206855
基因名称: TFR2
基因别名: HFE3; TFRC2
基因描述: Homo sapiens transferrin receptor 2 (TFR2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1893 (查看编码区序列)
翻译后氨基酸长度: 630 (查看氨基酸序列)
Transcript Variant: This variant (2) differs at the 5' end compared to variant 1, and initiates translation from an in-frame downstream AUG, resulting in an isoform (2, also known as beta) with a shorter N-terminus (lacking the transmembrane domain) compared to isoform 1. While there is transcript support for this variant (PMID:10409623), the protein is predicted.

订购信息

产品编号 产品名称 载体 规格 价格
G161870 人 TFR2 (NM_001206855) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TFR2 (NM_003227) cDNA克隆 transcript variant 1
人 TFR2 (NM_001206855) cDNA克隆 transcript variant 2

基因简介

This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]

相关产品