人 RNF4 (NM_001185010) cDNA克隆

Accession: NM_001185010
基因名称: RNF4
基因别名: SLX5; SNURF; RES4-26
基因描述: Homo sapiens ring finger protein 4 (RNF4), transcript variant 3, mRNA.
种属: Human
CDS区长度: 342 (查看编码区序列)
翻译后氨基酸长度: 113 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate exon in the 3' coding region which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.
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G157181 人 RNF4 (NM_001185010) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.[provided by RefSeq, Jul 2010]