This gene encodes a member of the phospholipid scramblase family. Phospholipid scramblases are membrane proteins that mediate calcium-dependent, non-specific movement of plasma membrane phospholipids and phosphatidylserine exposure. The encoded protein contains a low affinity calcium binding motif and may play a role in blood coagulation and apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
人 PLSCR2 (NM_001199979) cDNA克隆
| Accession: | NM_001199979 |
|---|---|
| 基因名称: | PLSCR2 |
| 基因描述: | Homo sapiens phospholipid scramblase 2 (PLSCR2), transcript variant 2, mRNA. |
| 种属: | Human |
| CDS区长度: | 882 (查看编码区序列) |
| 翻译后氨基酸长度: | 293 (查看氨基酸序列) |
| Transcript Variant: | This variant (2) differs in the 5' UTR and 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is shorter than isoform 1. |
| 人 PLSCR2 (NM_001199978) cDNA克隆 | transcript variant 1 |
| 人 PLSCR2 (NM_001199979) cDNA克隆 | transcript variant 2 |
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