人 PSG7 (NM_002783) cDNA克隆

Accession: NM_002783
基因名称: PSG7
基因别名: PSG1; PSGGA; PSBG-7
基因描述: Homo sapiens pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) (PSG7), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1260 (查看编码区序列)
翻译后氨基酸长度: 419 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). This version of transcript variant 1 retains a mismatch versus the reference genome sequence at codon 98 and represents the protein-coding minority allele. A second non-coding version of transcript variant 1 represents the major allele of this polymorphic locus and matches the reference genome sequence.
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G156131 人 PSG7 (NM_002783) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The reference genome contains a nonsense mutation that disrupts the coding sequence, suggesting that this gene may be evolving into a pseudogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]