人 EIF2AK2 (NM_001135652) cDNA克隆

基本信息

Accession: NM_001135652
基因名称: EIF2AK2
基因别名: PKR; PRKR; EIF2AK1
基因描述: Homo sapiens eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1533 (查看编码区序列)
翻译后氨基酸长度: 510 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. The 5' UTR splice pattern of this transcript has not been determined.

订购信息

产品编号 产品名称 载体 规格 价格
G155606 人 EIF2AK2 (NM_001135652) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 EIF2AK2 (NM_002759) cDNA克隆 transcript variant 1
人 EIF2AK2 (NM_001135651) cDNA克隆 transcript variant 2
人 EIF2AK2 (NM_001135652) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

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