人 THNSL2 (NM_001244676) cDNA克隆

基本信息

Accession: NM_001244676
基因名称: THNSL2
基因别名: THS2; TSH2; SOFAT
基因描述: Homo sapiens threonine synthase-like 2 (S. cerevisiae) (THNSL2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1218 (查看编码区序列)
翻译后氨基酸长度: 405 (查看氨基酸序列)
Transcript Variant: This variant (2) has a longer 5' UTR and uses an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G155252 人 THNSL2 (NM_001244676) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 THNSL2 (NM_018271) cDNA克隆 transcript variant 1
人 THNSL2 (NM_001244676) cDNA克隆 transcript variant 2
人 THNSL2 (NM_001244678) cDNA克隆 transcript variant 3

基因简介

This gene encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

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