人 XAF1 (NM_199139) cDNA克隆

Accession: NM_199139
基因名称: XAF1
基因别名: BIRC4BP; XIAPAF1; HSXIAPAF1
基因描述: Homo sapiens XIAP associated factor 1 (XAF1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 849 (查看编码区序列)
翻译后氨基酸长度: 282 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1.
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G155084 人 XAF1 (NM_199139) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]