Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 [PubMed 10753632]).[supplied by OMIM, Mar 2008]
人 TPCN1 (NM_017901) cDNA克隆
| Accession: | NM_017901 |
|---|---|
| 基因名称: | TPCN1 |
| 基因别名: | TPC1 |
| 基因描述: | Homo sapiens two pore segment channel 1 (TPCN1), transcript variant 2, mRNA. |
| 种属: | Human |
| CDS区长度: | 2451 (查看编码区序列) |
| 翻译后氨基酸长度: | 816 (查看氨基酸序列) |
| Transcript Variant: | This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. |
| 人 TPCN1 (NM_001143819) cDNA克隆 | transcript variant 1 |
| 人 TPCN1 (NM_017901) cDNA克隆 | transcript variant 2 |
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