人 PEG3 (NM_001146187) cDNA克隆

基本信息

Accession: NM_001146187
基因名称: PEG3
基因别名: PW1; ZNF904; ZSCAN24; ZKSCAN22
基因描述: Homo sapiens paternally expressed 3 (PEG3), transcript variant 5, mRNA.
种属: Human
CDS区长度: 4395 (查看编码区序列)
翻译后氨基酸长度: 1464 (查看氨基酸序列)
Transcript Variant: This variant (5) is missing a 5' non-coding exon, and uses alternate splice sites at several coding exons compared to variant 1. This results in the use of an in-frame downstream start codon, and an isoform (3) with a shorter N-terminus and two additional internal aa compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G154084 人 PEG3 (NM_001146187) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PEG3 (NM_006210) cDNA克隆 transcript variant 1
人 PEG3 (NM_001146184) cDNA克隆 transcript variant 2
人 PEG3 (NM_001146185) cDNA克隆 transcript variant 3
人 PEG3 (NM_001146186) cDNA克隆 transcript variant 4
人 PEG3 (NM_001146187) cDNA克隆 transcript variant 5

基因简介

In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2009]

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