人 PDE8A (NM_001243137) cDNA克隆

基本信息

Accession: NM_001243137
基因名称: PDE8A
基因别名: HsT19550
基因描述: Homo sapiens phosphodiesterase 8A (PDE8A), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2274 (查看编码区序列)
翻译后氨基酸长度: 757 (查看氨基酸序列)
Transcript Variant: This variant (3) contains an alternate 5' terminal exon compared to variant 1. This results in translation initiation from an in-frame downstream AUG, and an isoform (3) with a shorter N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G153996 人 PDE8A (NM_001243137) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PDE8A (NM_002605) cDNA克隆 transcript variant 1
人 PDE8A (NM_173454) cDNA克隆 transcript variant 2
人 PDE8A (NM_001243137) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]

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