人 PDE1A (NM_001003683) cDNA克隆

基本信息

Accession: NM_001003683
基因名称: PDE1A
基因别名: HCAM1; HCAM-1; HSPDE1A; CAM-PDE-1A
基因描述: Homo sapiens phosphodiesterase 1A, calmodulin-dependent (PDE1A), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1608 (查看编码区序列)
翻译后氨基酸长度: 535 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' and 3' UTRs, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G153937 人 PDE1A (NM_001003683) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PDE1A (NM_005019) cDNA克隆 transcript variant 1
人 PDE1A (NM_001003683) cDNA克隆 transcript variant 2
人 PDE1A (NM_001258312) cDNA克隆 transcript variant 3
人 PDE1A (NM_001258313) cDNA克隆 transcript variant 4
人 PDE1A (NM_001258314) cDNA克隆 transcript variant 5

基因简介

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009]

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