人 GP6 (NM_016363) cDNA克隆

基本信息

Accession: NM_016363
基因名称: GP6
基因别名: GPIV; GPVI; BDPLT11
基因描述: Homo sapiens glycoprotein VI (platelet) (GP6), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1020 (查看编码区序列)
翻译后氨基酸长度: 339 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1, that results in a frameshift. It encodes isoform 2 which has a shorter and distinct C-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G153880 人 GP6 (NM_016363) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GP6 (NM_001083899) cDNA克隆 transcript variant 1
人 GP6 (NM_016363) cDNA克隆 transcript variant 2
人 GP6 (NM_001256017) cDNA克隆 transcript variant 3

基因简介

This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

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