人 MLLT4 (NM_001040000) cDNA克隆

Accession: NM_001040000
基因名称: MLLT4
基因别名: AF6; RP3-431P23.3
基因描述: Homo sapiens myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 (MLLT4), transcript variant 2, mRNA.
种属: Human
CDS区长度: 4956 (查看编码区序列)
翻译后氨基酸长度: 1651 (查看氨基酸序列)
Transcript Variant: This variant (2) has several differences, including the presence of an in-frame coding exon, and the absence of several coding exons from the 3' end compared to variant 1. This results in an isoform (2) with a different and shorter C-terminus compared to isoform 1.
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G152424 人 MLLT4 (NM_001040000) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized.[provided by RefSeq, May 2011]