Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]
Accession: | NM_013255 |
---|---|
基因名称: | MKLN1 |
基因别名: | TWA2 |
基因描述: | Homo sapiens muskelin 1, intracellular mediator containing kelch motifs (MKLN1), transcript variant 2, mRNA. |
种属: | Human |
CDS区长度: | 2208 (查看编码区序列) |
翻译后氨基酸长度: | 735 (查看氨基酸序列) |
Transcript Variant: | This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is longer than isoform 1. |
人 MKLN1 (NM_001145354) cDNA克隆 | transcript variant 1 |
人 MKLN1 (NM_013255) cDNA克隆 | transcript variant 2 |
Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]