人 IKBKB (NM_001190720) cDNA克隆

Accession: NM_001190720
基因名称: IKBKB
基因别名: IKK2; IKKB; NFKBIKB; IKK-beta
基因描述: Homo sapiens inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2265 (查看编码区序列)
翻译后氨基酸长度: 754 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon in the 5' region, resulting in an upstream AUG start codon, as compared to variant 1. The resulting isoform (2) is slightly shorter and has a different N-terminus, as compared to isoform 1.
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G150008 人 IKBKB (NM_001190720) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011]