人 IGFBP7 (NM_001253835) cDNA克隆

基本信息

Accession: NM_001253835
基因名称: IGFBP7
基因别名: AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1
基因描述: Homo sapiens insulin-like growth factor binding protein 7 (IGFBP7), transcript variant 2, mRNA.
种属: Human
CDS区长度: 840 (查看编码区序列)
翻译后氨基酸长度: 279 (查看氨基酸序列)
Transcript Variant: This variant (2) differs at the 3' end, and lacks the 3' terminal exon compared to variant 1. This results in a frame-shift, and a shorter isoform (2) with a distinct C-terminus compared to isoform 1. Expression of this variant has been associated with retinal arterial macroaneurysm (PMID:21835307).

订购信息

产品编号 产品名称 载体 规格 价格
G149920 人 IGFBP7 (NM_001253835) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IGFBP7 (NM_001553) cDNA克隆 transcript variant 1
人 IGFBP7 (NM_001253835) cDNA克隆 transcript variant 2

基因简介

This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]

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