人 IARS (NM_013417) cDNA克隆

Accession: NM_013417
基因名称: IARS
基因别名: IRS; ILRS; IARS1; ILERS; PRO0785
基因描述: Homo sapiens isoleucyl-tRNA synthetase (IARS), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3789 (查看编码区序列)
翻译后氨基酸长度: 1262 (查看氨基酸序列)
Transcript Variant: This variant (2) has an alternate splice site in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
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G149623 人 IARS (NM_013417) cDNA克隆 pDONR223 2ug质粒 点击询价

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. [provided by RefSeq, Nov 2012]