人 TLX1 (NM_001195517) cDNA克隆

Accession: NM_001195517
基因名称: TLX1
基因别名: TCL3; HOX11
基因描述: Homo sapiens T-cell leukemia homeobox 1 (TLX1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 774 (查看编码区序列)
翻译后氨基酸长度: 257 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which has a shorter C-terminus, compared to isoform 1.
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G148957 人 TLX1 (NM_001195517) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]