人 GUK1 (NM_001159391) cDNA克隆

基本信息

Accession: NM_001159391
基因名称: GUK1
基因别名: GMK
基因描述: Homo sapiens guanylate kinase 1 (GUK1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 594 (查看编码区序列)
翻译后氨基酸长度: 197 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence and contains an alternate coding exon in the 3' end compared to variant 5, that causes a frameshift. The resulting isoform (b) is shorter at the N-terminus and has a shorter and distinct C-terminus compared to isoform c. Variants 2, 3, and 4 all encode the same isoform.

订购信息

产品编号 产品名称 载体 规格 价格
G147178 人 GUK1 (NM_001159391) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 GUK1 (NM_001159390) cDNA克隆 transcript variant 1
人 GUK1 (NM_000858) cDNA克隆 transcript variant 2
人 GUK1 (NM_001159391) cDNA克隆 transcript variant 3
人 GUK1 (NM_001242839) cDNA克隆 transcript variant 4
人 GUK1 (NM_001242840) cDNA克隆 transcript variant 5

基因简介

The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

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