大鼠 Bag1 (NM_001106647) cDNA克隆

Accession: NM_001106647
基因名称: Bag1
基因别名: Bag-1
基因描述: Rattus norvegicus BCL2-associated athanogene (Bag1), transcript variant 1, mRNA.
种属: Rat
CDS区长度: 1077 (查看编码区序列)
翻译后氨基酸长度: 358 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes multiple isoforms due to the use of alternative translation initiation codons. The longer isoform (BAG-1L or p50) is derived from an upstream non-AUG (CUG) start codon, while the shorter isoform (BAG-1S or p32) is derived from a downstream AUG start codon. The longer isoform (1L) is represented in this RefSeq.
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G147065 大鼠 Bag1 (NM_001106647) cDNA克隆 pDONR223 2ug质粒 点击询价

The oncogene Bcl2 encodes a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. Studies in human and mouse suggest that the protein encoded by this gene (referred to as Bcl2-associated athanogene) binds to Bcl2 protein. It enhances the anti-apoptotic effects of Bcl2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least two protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site and an alternative, downstream, AUG translation initiation site. [provided by RefSeq, Jul 2008]