人 RNF19A (NM_001280539) cDNA克隆

基本信息

Accession: NM_001280539
基因名称: RNF19A
基因别名: RNF19
基因描述: Homo sapiens ring finger protein 19A, RBR E3 ubiquitin protein ligase (RNF19A), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2517 (查看编码区序列)
翻译后氨基酸长度: 838 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same protein.

订购信息

产品编号 产品名称 载体 规格 价格
G143934 人 RNF19A (NM_001280539) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 RNF19A (NM_183419) cDNA克隆 transcript variant 1
人 RNF19A (NM_015435) cDNA克隆 transcript variant 2
人 RNF19A (NM_001280539) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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