人 PRKD2 (NM_001079882) cDNA克隆

Accession: NM_001079882
基因名称: PRKD2
基因别名: PKD2; HSPC187; nPKC-D2
基因描述: Homo sapiens protein kinase D2 (PRKD2), transcript variant 4, mRNA.
种属: Human
CDS区长度: 2166 (查看编码区序列)
翻译后氨基酸长度: 721 (查看氨基酸序列)
Transcript Variant: This variant (4) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (B) has a shorter N-terminus when compared to isoform A.
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G143634 人 PRKD2 (NM_001079882) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]