人 FUT8 (NM_004480) cDNA克隆

Accession: NM_004480
基因名称: FUT8
基因描述: Homo sapiens fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (FUT8), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1239 (查看编码区序列)
翻译后氨基酸长度: 412 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks a portion of the 5' UTR and 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a.
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G142686 人 FUT8 (NM_004480) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011]