大鼠 Aqp4 (NM_001270559) cDNA克隆

Accession: NM_001270559
基因名称: Aqp4
基因别名: Miwc; AQP-4; MIWC2; AQP4.M23
基因描述: Rattus norvegicus aquaporin 4 (Aqp4), transcript variant 4, mRNA.
种属: Rat
CDS区长度: 741 (查看编码区序列)
翻译后氨基酸长度: 246 (查看氨基酸序列)
Transcript Variant: This variant (4) contains an alternate exon at the 5' end, uses an in-frame downstream start codon, and lacks an alternate in-frame exon compared to variant 1. This results in an isoform (4, also known as AQP4d) with a shorter N-terminus and missing an alternate internal segment compared to isoform 1.
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G142675 大鼠 Aqp4 (NM_001270559) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene forms a water-specific channel that regulates body water balance, particularly in the brain. The encoded protein acts as a membrane-bound homotetramer, interacting with other proteins (MLC1, TRPV4, HEPACAM, and ATP1B1) to form a complex. Several variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]