人 KAT6B (NM_001256469) cDNA克隆

基本信息

Accession: NM_001256469
基因名称: KAT6B
基因别名: qkf; MORF; MOZ2; GTPTS; MYST4; ZC2HC6B; querkopf
基因描述: Homo sapiens K(lysine) acetyltransferase 6B (KAT6B), transcript variant 3, mRNA.
种属: Human
CDS区长度: 5346 (查看编码区序列)
翻译后氨基酸长度: 1781 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G140863 人 KAT6B (NM_001256469) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 KAT6B (NM_012330) cDNA克隆 transcript variant 1
人 KAT6B (NM_001256468) cDNA克隆 transcript variant 2
人 KAT6B (NM_001256469) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

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