人 FOLR2 (NM_000803) cDNA克隆

基本信息

Accession: NM_000803
基因名称: FOLR2
基因别名: FBP; FR-P3; FR-BETA; BETA-HFR; FBP/PL-1
基因描述: Homo sapiens folate receptor 2 (fetal) (FOLR2), transcript variant 1, mRNA.
种属: Human
CDS区长度: 768 (查看编码区序列)
翻译后氨基酸长度: 255 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript. All variants (1-4) encode the same protein.

订购信息

产品编号 产品名称 载体 规格 价格
G140815 人 FOLR2 (NM_000803) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 FOLR2 (NM_000803) cDNA克隆 transcript variant 1
人 FOLR2 (NM_001113534) cDNA克隆 transcript variant 2
人 FOLR2 (NM_001113535) cDNA克隆 transcript variant 3
人 FOLR2 (NM_001113536) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

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