人 PHF8 (NM_001184897) cDNA克隆

基本信息

Accession: NM_001184897
基因名称: PHF8
基因别名: JHDM1F; MRXSSD; ZNF422
基因描述: Homo sapiens PHD finger protein 8 (PHF8), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2847 (查看编码区序列)
翻译后氨基酸长度: 948 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence, the 3' UTR and coding sequence, and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (3) has a shorter N-terminus, longer and distinct C-terminus, and lacks an internal segment compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G140153 人 PHF8 (NM_001184897) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PHF8 (NM_001184896) cDNA克隆 transcript variant 1
人 PHF8 (NM_015107) cDNA克隆 transcript variant 2
人 PHF8 (NM_001184897) cDNA克隆 transcript variant 3
人 PHF8 (NM_001184898) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

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