人 FKBP5 (NM_004117) cDNA克隆

基本信息

Accession: NM_004117
基因名称: FKBP5
基因别名: P54; AIG6; FKBP51; FKBP54; PPIase; Ptg-10
基因描述: Homo sapiens FK506 binding protein 5 (FKBP5), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1374 (查看编码区序列)
翻译后氨基酸长度: 457 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the shortest transcript and encodes the longer isoform (1). Variants 1, 2 and 3 encode the same isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G139670 人 FKBP5 (NM_004117) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 FKBP5 (NM_004117) cDNA克隆 transcript variant 1
人 FKBP5 (NM_001145775) cDNA克隆 transcript variant 2
人 FKBP5 (NM_001145776) cDNA克隆 transcript variant 3
人 FKBP5 (NM_001145777) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

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