小鼠 Vegfa (NM_001025257) cDNA克隆

基本信息

Accession: NM_001025257
基因名称: Vegfa
基因别名: Vpf; Vegf
基因描述: Mus musculus vascular endothelial growth factor A (Vegfa), transcript variant 3, mRNA.
种属: Mouse
CDS区长度: 975 (查看编码区序列)
翻译后氨基酸长度: 324 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks two consecutive in-frame exons in the coding region, compared to variant 1. This variant can initiate translation from non-AUG (CUG) site, and also from a downstream, in-frame AUG site. The isoform (3) represented in this RefSeq is derived from the CUG start codon and it lacks an internal segment, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G138743 小鼠 Vegfa (NM_001025257) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

小鼠 Vegfa (NM_001025250) cDNA克隆 transcript variant 1
小鼠 Vegfa (NM_001287056) cDNA克隆 transcript variant 1
小鼠 Vegfa (NM_009505) cDNA克隆 transcript variant 2
小鼠 Vegfa (NM_001287057) cDNA克隆 transcript variant 2
小鼠 Vegfa (NM_001025257) cDNA克隆 transcript variant 3
小鼠 Vegfa (NM_001287058) cDNA克隆 transcript variant 3
小鼠 Vegfa (NM_001110266) cDNA克隆 transcript variant 4
小鼠 Vegfa (NM_001110267) cDNA克隆 transcript variant 5
小鼠 Vegfa (NM_001110268) cDNA克隆 transcript variant 6

基因简介

This gene product is a member of the PDGF/VEGF growth factor family. It is a mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Also, alternative translation initiation from non-AUG (CUG) and AUG start sites in some transcript variants, give rise to additional isoforms. The expression of some isoforms derived from AUG start codon is affected by a small upstream open reading frame, which is located within an internal ribosome entry site. [provided by RefSeq, Nov 2013]

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