人 UNC5B (NM_001244889) cDNA克隆

Accession: NM_001244889
基因名称: UNC5B
基因别名: UNC5H2; p53RDL1
基因描述: Homo sapiens unc-5 homolog B (C. elegans) (UNC5B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2805 (查看编码区序列)
翻译后氨基酸长度: 934 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate, in-frame, exon in the coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1.
产品编号 产品名称 载体 规格 价格
G138309 人 UNC5B (NM_001244889) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]