人 F2RL2 (NM_001256566) cDNA克隆

Accession: NM_001256566
基因名称: F2RL2
基因别名: PAR3; PAR-3
基因描述: Homo sapiens coagulation factor II (thrombin) receptor-like 2 (F2RL2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1059 (查看编码区序列)
翻译后氨基酸长度: 352 (查看氨基酸序列)
Transcript Variant: This variant (2) uses an alternate exon in the 5' UTR and coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.
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G137535 人 F2RL2 (NM_001256566) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]