人 EPS15 (NM_001981) cDNA克隆

Accession: NM_001981
基因名称: EPS15
基因别名: AF1P; AF-1P; MLLT5
基因描述: Homo sapiens epidermal growth factor receptor pathway substrate 15 (EPS15), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2691 (查看编码区序列)
翻译后氨基酸长度: 896 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (A). Isoform A mainly localizes to clathrin-coated pits at the plasma membrane.
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G136409 人 EPS15 (NM_001981) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009]