人 MARK2 (NM_004954) cDNA克隆

Accession: NM_004954
基因名称: MARK2
基因别名: EMK1; EMK-1; PAR-1; Par1b; Par-1b
基因描述: Homo sapiens MAP/microtubule affinity-regulating kinase 2 (MARK2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2175 (查看编码区序列)
翻译后氨基酸长度: 724 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks two alternate in-frame exons in the 3' coding region and uses an alternate in-frame splice site in the central coding region, compared to variant 4. The resulting isoform (c) lacks two internal segments and 1 internal residue, compared to isoform d.
产品编号 产品名称 载体 规格 价格
G135959 人 MARK2 (NM_004954) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]