人 ECT2 (NM_018098) cDNA克隆

基本信息

Accession: NM_018098
基因名称: ECT2
基因别名: ARHGEF31
基因描述: Homo sapiens epithelial cell transforming sequence 2 oncogene (ECT2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2652 (查看编码区序列)
翻译后氨基酸长度: 883 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode the same isoform (b).

订购信息

产品编号 产品名称 载体 规格 价格
G135059 人 ECT2 (NM_018098) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ECT2 (NM_001258315) cDNA克隆 transcript variant 1
人 ECT2 (NM_001258316) cDNA克隆 transcript variant 2
人 ECT2 (NM_018098) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene is a guanine nucleotide exchange factor and transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

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