人 DLG3 (NM_020730) cDNA克隆

Accession: NM_020730
基因名称: DLG3
基因别名: MRX; XLMR; MRX90; NEDLG; SAP102
基因描述: Homo sapiens discs, large homolog 3 (Drosophila) (DLG3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1539 (查看编码区序列)
翻译后氨基酸长度: 512 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. Translation initiates at an alternate AUG and results in an isoform (b) that is shorter and has a distinct N-terminus compared to isoform a.
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G134055 人 DLG3 (NM_020730) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked mental retardation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]