The protein encoded by this gene is part of the fatty acid binding protein family (FABP). FABPs are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands and participate in fatty acid uptake, transport, and metabolism. In humans this gene has been associated with psoriasis and type 2 diabetes. In mouse deficiency of this gene in combination with a deficiency in Fabp4 confers protection against atherosclerosis, diet-induced obesity, insulin resistance and experimental autoimmune encephalomyelitis (the mouse model for multiple sclerosis). Alternative splicing results in multiple transcript variants that encode different protein isoforms. The mouse genome contains many pseudogenes similar to this locus. [provided by RefSeq, Jan 2013]
小鼠 Fabp5 (NM_001272098) cDNA克隆
| Accession: | NM_001272098 |
|---|---|
| 基因名称: | Fabp5 |
| 基因别名: | Klbp; mal1; Fabpe; E-FABP; PA-FABP |
| 基因描述: | Mus musculus fatty acid binding protein 5, epidermal (Fabp5), transcript variant 3, mRNA. |
| 种属: | Mouse |
| CDS区长度: | 222 (查看编码区序列) |
| 翻译后氨基酸长度: | 73 (查看氨基酸序列) |
| Transcript Variant: | This variant (3) lacks an exon in the coding region, which results in a frameshift, compared to variant 1. Variant 3 lacks a large portion of the central coding region found in variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1. This isoform lacks the lipocalin domain found in isoform 1. |
| 小鼠 Fabp5 (NM_010634) cDNA克隆 | transcript variant 1 |
| 小鼠 Fabp5 (NM_001272097) cDNA克隆 | transcript variant 2 |
| 小鼠 Fabp5 (NM_001272098) cDNA克隆 | transcript variant 3 |
扫一扫 加微信
联系我们
- 客服热线:
0731-84158353 - 订货邮箱:
order@youbio.cn - 技术支持:
tech@youbio.cn 
QQ：2605877374
