人 IFNLR1 (NM_173065) cDNA克隆

基本信息

Accession: NM_173065
基因名称: IFNLR1
基因别名: IFNLR; LICR2; IL28RA; CRF2/12; IL-28R1
基因描述: Homo sapiens interferon, lambda receptor 1 (IFNLR1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 735 (查看编码区序列)
翻译后氨基酸长度: 244 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks one alternate segment and contains another in the 3' coding region which leads to a translation frameshift, as compared to variant 1. The resulting isoform (3) has a distinct and shorter C-terminus, as compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G132808 人 IFNLR1 (NM_173065) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IFNLR1 (NM_170743) cDNA克隆 transcript variant 1
人 IFNLR1 (NM_173064) cDNA克隆 transcript variant 2
人 IFNLR1 (NM_173065) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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