小鼠 Hck (NM_010407) cDNA克隆

Accession: NM_010407
基因名称: Hck
基因别名: Bmk; AI849071
基因描述: Mus musculus hemopoietic cell kinase (Hck), transcript variant 1, mRNA.
种属: Mouse
CDS区长度: 1575 (查看编码区序列)
翻译后氨基酸长度: 524 (查看氨基酸序列)
Transcript Variant: This transcript (1) encodes multiple isoforms due to the use of alternative translation initiation codons, as demonstrated in PMID:1875927. The longer isoform (p59Hck) is derived from an upstream non-AUG (CUG) start codon, while the shorter isoform (p56Hck) is derived from a downstream AUG start codon. The longer isoform (p59Hck) is represented in this RefSeq.
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G132125 小鼠 Hck (NM_010407) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may play a role in the innate immune response and the STAT5 signaling pathway. Alternative translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization. [provided by RefSeq, Feb 2010]