小鼠 Hap1 (NM_177981) cDNA克隆

基本信息

Accession: NM_177981
基因名称: Hap1
基因别名: HAP-1
基因描述: Mus musculus huntingtin-associated protein 1 (Hap1), transcript variant 2, mRNA.
种属: Mouse
CDS区长度: 1887 (查看编码区序列)
翻译后氨基酸长度: 628 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks a segment in the 3' coding region that causes a frameshift, and lacks a segment in the 3' UTR, compared to variant 1. The encoded protein (isoform B) is longer and has a distinct C-terminus, compared to isoform A.

订购信息

产品编号 产品名称 载体 规格 价格
G132096 小鼠 Hap1 (NM_177981) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

小鼠 Hap1 (NM_010404) cDNA克隆 transcript variant 1
小鼠 Hap1 (NM_177981) cDNA克隆 transcript variant 2

基因简介

The protein encoded by this gene was first identified as a neuronal protein that binds the HD protein huntingtin. The protein also interacts with kinesin light chain, 14-3-3 proteins, and Abelson helper integration site 1 protein. The protein is involved in intracellular trafficking of vesicles and organelles, and lack of the protein results in neuronal death resembling the hypothalamic degeneration that occurs in Huntington's disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

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