人 PPARGC1B (NM_001172698) cDNA克隆

基本信息

Accession: NM_001172698
基因名称: PPARGC1B
基因别名: PERC; ERRL1; PGC1B; PGC-1(beta)
基因描述: Homo sapiens peroxisome proliferator-activated receptor gamma, coactivator 1 beta (PPARGC1B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2955 (查看编码区序列)
翻译后氨基酸长度: 984 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G130414 人 PPARGC1B (NM_001172698) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PPARGC1B (NM_133263) cDNA克隆 transcript variant 1
人 PPARGC1B (NM_001172698) cDNA克隆 transcript variant 2
人 PPARGC1B (NM_001172699) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

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