人 ADH1B (NM_001286650) cDNA克隆

Accession: NM_001286650
基因名称: ADH1B
基因别名: ADH2
基因描述: Homo sapiens alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1008 (查看编码区序列)
翻译后氨基酸长度: 335 (查看氨基酸序列)
Transcript Variant: This variant (2) contains an alternate exon in the 5' end and uses a downstream start codon compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
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G129555 人 ADH1B (NM_001286650) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]